# atherosclerosis

/ˌæθɝoʊskɫɝˈoʊsɪs/ (US) · /ˌæθəɹˌɒskləɹˈəʊsɪs/ (UK) · CEFR C1 · Noun

Source: https://englishreference.com/word/atherosclerosis
Updated: 2026-05-26

## Definition

a medical condition where the walls of your arteries become thick and stiff. This happens because of a build-up of fat and other substances, which can make it harder for blood to flow through your body.

For teachers: a chronic inflammatory disease of the arteries characterised by the accumulation of fatty plaques within the arterial walls. This process leads to the narrowing and hardening of the vessels, potentially resulting in reduced blood flow and increased cardiovascular risk.

## Examples

- High cholesterol levels are a major risk factor for atherosclerosis.
- The doctor explained that atherosclerosis in the coronary arteries can eventually lead to a heart attack if left untreated.
- While atherosclerosis is often associated with aging, lifestyle factors such as smoking, poor diet, and lack of exercise can significantly accelerate the progression of the disease in younger populations.

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