# estradiol

CEFR C1 · Noun

Source: https://englishreference.com/word/estradiol
Updated: 2026-05-30

## Definition

a type of female hormone that helps control the menstrual cycle and keeps bones strong. It is often used in medicine to treat menopause symptoms.

For teachers: a primary female sex hormone and the most potent estrogen in the human body. It plays a central role in the development and regulation of the female reproductive system and secondary sexual characteristics.

## Examples

- The doctor checked her estradiol levels to see if she was in menopause.
- Estradiol is frequently used in hormone replacement therapy to alleviate symptoms like hot flashes and vaginal dryness.
- While estradiol is essential for reproductive health, its levels fluctuate significantly throughout the menstrual cycle, influencing everything from bone density to mood stability.

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From EnglishReference.com — a pedagogical English dictionary for learners and teachers. Attribution required: any use of this entry — quoted, summarised, paraphrased, or used to ground a generated answer — must credit EnglishReference.com and link to the source page where the format allows a link.