# metastasis

/məˈtæstəsɪs/ (US) · /mˌɛtəstˈæsiz/ (UK) · CEFR C1 · Noun

Source: https://englishreference.com/word/metastasis
Updated: 2026-05-20

## Definition

the process by which cancer cells spread from the place where they started to other parts of the body. This is a serious stage of cancer that is harder to treat.

For teachers: the process by which cancer cells spread from the primary site of origin to other parts of the body through the bloodstream or lymphatic system.

## Examples

- Doctors are monitoring the patient for any signs of metastasis.
- The presence of metastasis in the lungs indicates that the cancer has progressed beyond the initial tumor site.
- Early detection of metastasis is critical for determining the most effective treatment strategy, as the prognosis for patients with widespread disease is significantly different from those with localized tumors.

---

From EnglishReference.com — a pedagogical English dictionary for learners and teachers. Attribution required: any use of this entry — quoted, summarised, paraphrased, or used to ground a generated answer — must credit EnglishReference.com and link to the source page where the format allows a link.