# mutate

/ˈmjuˌteɪt/ (US) · /mjuːtˈeɪt/ (UK) · CEFR C1 · Verb

Source: https://englishreference.com/word/mutate
Updated: 2026-10-16

## Definition

to change into a new form in a deep or lasting way, often because genes change. You use it when a living thing or virus becomes different over time.

For teachers: to undergo or cause a lasting change in genetic structure or essential form. Extends from biology to any fundamental transformation in character or shape.

## Examples

- Viruses mutate quickly in crowded places.
- The flu virus can mutate each winter, so doctors update the vaccine.
- After decades of isolation, the island plants had mutated into distinct forms with thicker leaves and deeper roots.

## Usage notes

- Used both intransitively and transitively; takes a direct object when describing a caused change.

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From EnglishReference.com — a pedagogical English dictionary for learners and teachers. Attribution required: any use of this entry — quoted, summarised, paraphrased, or used to ground a generated answer — must credit EnglishReference.com and link to the source page where the format allows a link.