# novo

/ˈnoʊvoʊ/ (US) · CEFR C2 · Adjective

Source: https://englishreference.com/word/novo
Updated: 2026-05-07

## Definition

starting from the beginning again, especially when you create something completely new instead of changing what already exists.

For teachers: starting from the beginning; anew. Often describes biological or chemical processes occurring for the first time rather than being inherited or recycled.

## Examples

- The scientists observed de novo protein synthesis in the lab.
- Instead of updating the old software, the team decided to build a de novo system from scratch.
- The court ordered a de novo trial, meaning the case would be heard again as if the previous legal proceedings had never occurred.

## Usage notes

- Borrowed from Latin; almost always appears as part of the phrase 'de novo'. Typically functions as an adjective or adverb following the noun it modifies.

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From EnglishReference.com — a pedagogical English dictionary for learners and teachers. Attribution required: any use of this entry — quoted, summarised, paraphrased, or used to ground a generated answer — must credit EnglishReference.com and link to the source page where the format allows a link.