# sepsis

/ˈsɛpsɪs/ (US) · /sˈɛpsɪs/ (UK) · CEFR C2 · Noun

Source: https://englishreference.com/word/sepsis
Updated: 2026-05-11

## Definition

a very dangerous reaction your body has to an infection. It happens when your immune system attacks your own organs while trying to fight off germs.

For teachers: a life-threatening systemic inflammatory response syndrome triggered by an infection. Characterised by organ dysfunction resulting from a dysregulated host response to pathogens.

## Examples

- The patient was rushed to the hospital with signs of sepsis.
- Early diagnosis of sepsis is critical because the condition can lead to rapid organ failure if not treated with antibiotics immediately.
- Medical professionals are trained to monitor for the clinical markers of sepsis, as the transition from a localized infection to a systemic crisis can occur with alarming speed.

## Usage notes

- Typically used in medical contexts; often follows verbs like 'develop' or 'prevent'.

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From EnglishReference.com — a pedagogical English dictionary for learners and teachers. Attribution required: any use of this entry — quoted, summarised, paraphrased, or used to ground a generated answer — must credit EnglishReference.com and link to the source page where the format allows a link.