go down the drain

all dressed up and nowhere to go

Elaborately attired or otherwise fully prepared for an anticipated situation or activity which, nevertheless, fails to occur.

all systems go

Everything is ready.

as you go

While one is doing (something); as one progresses.

boldly go where no man has gone before

To break new ground.

brain drain

The migration of educated or talented people from less economically advanced areas to more economically advanced areas, especially to large cities or more developed nations.

circle the drain

To be in a rapid decline or in a state of downfall, especially as leading to an inevitable utter failure or destruction.

come and go

To repeatedly appear and disappear; to be transient.

don't go there

Do not broach that topic.