nature abhors a vacuum
idiomGenerating and maintaining a near-vacuum is challenging (requiring technical rigor) because ambient pressure tends to push matter forcefully into the evacuated chamber; and generating a true vacuum (devoid of any matter at all) is extremely challenging.
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answer the call of nature
To satisfy a bodily urge to urinate or defecate.
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better nature
the more amiable qualities of someone
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let nature take its course
To permit events to proceed or a situation to develop without intervention or interference.
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nature calls
Used to indicate that someone (usually the speaker) feels a need to urinate or defecate.
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nature of the beast
The unchangeable nature of something.
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second nature
A mindset, skill, or type of behavior so ingrained through habit or practice that it seems natural, automatic, or without a basis in conscious thought.