acantholysis
n. C2 Proficiency acan·thol·y·sis
n. a medical condition where the skin cells that hold the skin together start to separate. This often causes the skin to look loose or blister.
n. the separation of epidermal cells from one another, resulting in the loss of cohesion between the keratinocytes. This process is a hallmark of certain autoimmune blistering disorders.
The doctor diagnosed the skin condition as acantholysis.
In pemphigus vulgaris, acantholysis occurs between the cells of the epidermis, leading to the formation of painful blisters.
The histological examination revealed acantholysis, confirming the presence of a blistering disease that requires immediate immunosuppressive therapy to prevent further tissue damage.