English Reference

Word

antidepressant

Phoneticsan·tide·pres·sant

US/ˌæntidɪˈpɹɛsənt/

UK/ˌæntɪdɪpɹˈɛsənt/

Definition

n. a type of medicine that doctors prescribe to help people feel better when they are sad or have very low energy for a long time.

n. a class of medication used to treat clinical depression and other mood disorders by altering brain chemistry.

Examples

“The doctor prescribed an antidepressant to help him sleep better.”

“After several weeks of taking the antidepressant, she noticed a significant improvement in her ability to concentrate at work.”

“While antidepressants are effective for many patients, they often require several weeks of consistent use before the full therapeutic benefits become apparent in the brain's neural pathways.”

Examples

simple

“The doctor prescribed an antidepressant to help him sleep better.”

contextual

“After several weeks of taking the antidepressant, she noticed a significant improvement in her ability to concentrate at work.”

complex

“While antidepressants are effective for many patients, they often require several weeks of consistent use before the full therapeutic benefits become apparent in the brain's neural pathways.”

Real-World Examples

Common in culture and health writing

“When I was pregnant with my son, I continued taking the antidepressant citalopram.”
The Guardian · 22 Aug 2026
“If multiple antidepressants haven’t helped, there are other avenues to explore.”
The New York Times · 20 Aug 2026

Etymology

From anti- + depressant.

Etymology adapted from Wiktionary, available under CC BY-SA 4.0.

Word family

antidepressantNoundepressVerb

This entry

Level
B2 · Upper Intermediate
Frequency
Occasional
Updated

Scan code

englishreference.com/q/antidepressant

English Reference