English Reference

Word

antigen

Phoneticsanti·gen

US/ˈæntədʒən/

UK/ˈæntɪdʒˌɛn/

Definition

n. a substance that makes your immune system start fighting, often by creating antibodies. It is usually something from outside your body, like a virus or bacteria.

n. any substance that induces an immune response in the body, specifically the production of antibodies. Typically a protein or polysaccharide on the surface of a pathogen.

Examples

“The vaccine introduces a harmless antigen to your body.”

“Doctors use a rapid test to detect the presence of a specific viral antigen in the patient's blood sample.”

“The immune system distinguishes between self and non-self by recognizing unique molecular patterns on the surface of the invading antigen, triggering a targeted defensive response.”

Examples

simple

“The vaccine introduces a harmless antigen to your body.”

contextual

“Doctors use a rapid test to detect the presence of a specific viral antigen in the patient's blood sample.”

complex

“The immune system distinguishes between self and non-self by recognizing unique molecular patterns on the surface of the invading antigen, triggering a targeted defensive response.”

Usage

Commonly used in medical and biological contexts; often paired with verbs like 'detect', 'recognize', or 'bind'.

Real-World Examples

“Researchers used artificial intelligence and machine learning to design what they call a "super-antigen." The antigen is the component of a vaccine that trains the immune system to recognize and fight infection.”
ScienceDaily · 5 Jun 2026
“Antigens are the critical components of vaccines as this is what the immune system learns to attack.”
BBC News · 4 Jun 2026
“The whole-cell pertussis vaccine used in the 1980s alone contained roughly 3,000 antigens .”
The Conversation · 12 Aug 2026

Etymology

From French antigène, from anti- + gène.

Etymology adapted from Wiktionary, available under CC BY-SA 4.0.

This entry

Level
C1 · Advanced
Frequency
Frequent
Updated

Scan code

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English Reference