blockade
n.-
1 military/naval isolation (n.) C1 Advanced Formalthe use of ships or soldiers to block a port or city so that nothing can go in or out.
the physical isolation of a location, particularly a port, by hostile forces to prevent the passage of commerce and supplies.
ExampleThe navy set up a blockade to stop supplies from reaching the enemy port.
ExampleThe government maintained a strict naval blockade for several months, effectively crippling the city's economy by preventing the export of local goods.
UsageOften used with the verbs 'impose', 'lift', or 'break'.
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2 medical/biological inhibition (n.) C2 Proficiency Technical Medicinethe act of stopping a chemical or nerve signal from working in the body.
the inhibition of the physiological activity of a chemical messenger or its receptor, often through the use of drugs.
ExampleThe doctor used a nerve blockade to stop the patient from feeling pain during the procedure.
ExampleThe pharmacological blockade of beta-adrenergic receptors is a standard treatment for managing certain cardiovascular conditions.
UsageCommonly appears in the context of 'receptor blockade' or 'nerve blockade'.
From block + -ade, probably after Dutch blocquade (now blokkade) or German Blockade.