English Reference

Word

cholesterol

Phoneticscholes·terol

US/kəˈɫɛstɝˌɔɫ/

UK/kəlˈɛstəɹˌɒl/

Definitions

01the biological substance

B2 · Science

n. a fatty substance that your body makes and uses to build cells.

n. a sterol lipid synthesized by the liver that is a structural component of animal cell membranes and a precursor for steroid hormones.

“The body needs a certain amount of cholesterol to build healthy cells.”

“Cholesterol plays a vital role in maintaining the fluidity of the plasma membrane across a range of physiological temperatures.”

Technical

Synonyms

lipidfatty acid

02the medical measurement

B2 · Medicine

n. the amount of this fatty substance in your blood, often checked by a doctor.

n. the concentration of various lipoproteins in the blood, typically measured to assess the risk of heart disease.

“He changed his diet because his doctor said his cholesterol was too high.”

“Regular blood tests are necessary to monitor her cholesterol, especially since she has a family history of cardiovascular issues.”

Usage

Often used uncountably when referring to the general health marker.

Synonyms

cholesterol levellipid profile

Real-World Examples

“But it is largely preventable through a healthy lifestyle -- including regular physical activity, a heart-healthy diet, not smoking, maintaining a healthy weight, and managing blood pressure, cholesterol, and diabetes.”
ScienceDaily · 14 Aug 2026
“It includes three behavioral factors (healthy diet, non-smoking, and physical activity) and four health factors (blood pressure, body mass index, total cholesterol and fasting blood glucose).”
ScienceDaily · 16 Aug 2026

Etymology

Borrowed from French cholestérol.

Etymology adapted from Wiktionary, available under CC BY-SA 4.0.

This entry

Level
B2 · Upper Intermediate
Frequency
Frequent
Updated

Scan code

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English Reference