English Reference

Word

cortisol

Phoneticscor·ti·sol

US/ˈkɔɹtɪˌsɔɫ/

UK/kˈɔːtɪsˌɒl/

Definitions

01the stress hormone

C1 · Science

n. a natural chemical in your body that increases when you are under pressure or feeling stressed.

n. a glucocorticoid hormone produced by the adrenal glands that mediates metabolic processes and increases in response to physical or psychological stress.

“High levels of cortisol can make it very difficult to get a good night's sleep.”

“Chronic elevation of cortisol levels is associated with a range of adverse health outcomes, including impaired immune function and increased abdominal fat storage.”

Technical

Usage

Uncountable when referring to the hormone generally; countable when referring to specific measurements or types.

Teaching tip

While technically a biological term, it is now common in general health and wellness discussions to describe the physical effects of stress.

Synonyms

hydrocortisone

02slang for stress

C2

n. a modern way to talk about feeling stressed or anxious.

n. a metonymic use where the name of the hormone represents the state of stress or anxiety itself.

“My cortisol is so high right now because of all these deadlines.”

“The constant notifications on her phone were spiking her cortisol throughout the entire workday.”

Informal · Slang

Usage

Often used with verbs like 'spike', 'raise', or 'lower' in a non-medical context.

Teaching tip

This usage is very common in social media and 'wellness' culture to describe a general feeling of being overwhelmed.

Antonyms

Real-World Examples

“Frequent cannabis users may wake up with unusually high levels of the stress hormone cortisol, suggesting their daily stress rhythms could be disrupted.”
ScienceDaily · 9 Aug 2026
“Higher levels of cortisol also worsens sleep further, locking workers into a self-reinforcing cycle.”
BBC News · 19 Jul 2026

Etymology

From cortisone + -ol.

Etymology adapted from Wiktionary, available under CC BY-SA 4.0.

This entry

Level
C1 · Advanced
Frequency
Occasional
Updated

Scan code

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English Reference