incompatibility
n. uncountablen. the state of being unable to work together or exist in the same place. It often describes things like software that won't run on a new computer or people who cannot get along.
n. the state of being unable to exist, work, or function together; a lack of compatibility. Often used in technical contexts to describe software or hardware conflicts, or in social contexts to describe interpersonal friction.
The new software caused incompatibility with my old operating system.
The doctor warned that the patient's body showed signs of incompatibility with the donated organ.
The project failed not because of a lack of resources, but due to the fundamental incompatibility between the two corporate cultures.
From incompatible + -ity.