English Reference

Word

isotope

Phoneticsiso·tope

US/ˈaɪsəˌtoʊp/

UK/ˈaɪsətˌəʊp/

Definition

n. a form of a chemical element that has the same number of protons but a different number of neutrons.

n. any of two or more forms of a chemical element where the atoms have the same number of protons but a different number of neutrons within their nuclei.

Examples

“Carbon-14 is a famous isotope used to find the age of old objects.”

“Scientists analyzed the oxygen isotope ratios in the ice core to determine historical temperature fluctuations.”

“The medical team utilized a specific radioactive isotope for the diagnostic scan, ensuring the tracer would decay rapidly enough to minimize the patient's overall radiation exposure.”

Examples

simple

“Carbon-14 is a famous isotope used to find the age of old objects.”

contextual

“Scientists analyzed the oxygen isotope ratios in the ice core to determine historical temperature fluctuations.”

complex

“The medical team utilized a specific radioactive isotope for the diagnostic scan, ensuring the tracer would decay rapidly enough to minimize the patient's overall radiation exposure.”

Usage

Countable noun; often identified by the element name followed by the mass number.

Teaching tip

While this is a highly technical term, it is essential for students discussing archaeology, nuclear energy, or advanced biology.

Real-World Examples

“To trace where these compounds came from, the researchers labeled proteins with stable (non-radioactive) isotopes and followed their digestion in the mouse gut.”
ScienceDaily · 15 Aug 2026
“In particular, the researchers measured strontium isotopes in tooth enamel.”
Phys.org · 15 Aug 2026

Etymology

From iso- (“equal”) + -tope (“place”), because the different isotopes of an element always occupy the same place in the periodic table. The term was coined by Scottish doctor Margaret Todd in 1909 and first used publicly on February 27, 1913 by English chemist Frederick Soddy.

Possible back-formation from isotopy.

Etymology adapted from Wiktionary, available under CC BY-SA 4.0.

Synonyms

variantnuclide

This entry

Level
C1 · Advanced
Frequency
Occasional
Updated
Register
Technical

Scan code

englishreference.com/q/isotope

English Reference