ENGLISH
REFERENCE

ligand

n. countable
C2 Proficiency US //ˈɫɪɡənd// lig·and

n. a molecule that binds to a specific site on a larger molecule, like a protein. This connection often sends a signal to a cell or causes a chemical change.

n. a molecule or ion that binds specifically to a receptor or central metal atom to form a complex. In pharmacology, it acts as a signaling molecule that triggers a biological response upon binding.


SIMPLE

The ligand attaches to the cell receptor.

CONTEXTUAL

Researchers are developing a new ligand that can target cancer cells without affecting healthy tissue.

COMPLEX

The binding affinity of the ligand determines how effectively the drug can compete with natural hormones for the same receptor site within the nervous system.

Origin

Borrowed from Latin ligandus, gerundive of ligo (“bind”).

Usage

Commonly used in biochemistry and pharmacology; often paired with the verb 'bind' and the preposition 'to'.

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