English Reference

Word

melanoma

US/ˌmɛɫəˈnoʊmə/

UK/mˌɛlɐnˈəʊmɐ/

Definition

n. a serious type of skin cancer that often starts in a mole. It happens when the cells that give your skin its color grow out of control.

n. a malignant tumour of melanocytes, typically occurring in the skin but also found in the eyes or intestines. It is characterized by the uncontrolled growth of pigment-producing cells and carries a high risk of metastasis.

Examples

“Early detection of melanoma is vital for successful treatment.”

“The dermatologist performed a biopsy on the irregular mole to check for signs of melanoma.”

“While melanoma is less common than other forms of skin cancer, it is significantly more aggressive and accounts for the majority of skin cancer-related deaths globally.”

Examples

simple

“Early detection of melanoma is vital for successful treatment.”

contextual

“The dermatologist performed a biopsy on the irregular mole to check for signs of melanoma.”

complex

“While melanoma is less common than other forms of skin cancer, it is significantly more aggressive and accounts for the majority of skin cancer-related deaths globally.”

Usage

Uncountable when referring to the disease generally; countable when referring to a specific instance or lesion.

Real-World Examples

Common in health and science writing

“Moderna and Merck say the experimental vaccine prevented the return and spread of the cancer in high-risk melanoma patients.”
The New York Times · 19 Aug 2026
“The vaccine, developed by drug companies Merck and Moderna, was given to patients with high-risk melanoma, a type of skin cancer, after they had surgery.”
BBC News · 19 Aug 2026
“Image caption, The i Paper's top story also covers the landmark vaccine trial, which found patients with high-risk melanoma remained free of cancer for longer after surgery.”
BBC News · 20 Aug 2026
“Geological Survey (USGS) and the Vermont Fish and Wildlife Department confirmed the lesions were malignant melanoma .”
Phys.org · 19 Aug 2026

Etymology

From melano- + -oma.

Etymology adapted from Wiktionary, available under CC BY-SA 4.0.

This entry

Level
C2 · Proficiency
Frequency
Occasional
Updated

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English Reference