ENGLISH
REFERENCE

progesterone

n. uncountable
C1 Advanced US //pɹoʊˈdʒɛstɝˌoʊn// UK //pɹəʊdʒˈɛstəɹˌəʊn// pro·ges·terone

n. a natural hormone in the body that helps manage the menstrual cycle and supports pregnancy.

n. a steroid hormone secreted by the corpus luteum and the placenta that prepares the uterus for the implantation of a fertilized ovum and maintains pregnancy.


SIMPLE

The doctor checked her progesterone levels during the first trimester.

CONTEXTUAL

A drop in progesterone levels usually signals the body to begin the menstrual cycle.

COMPLEX

In addition to its reproductive functions, progesterone acts as a neurosteroid in the brain, influencing mood and sleep patterns through its interaction with various neurotransmitter systems.

Origin

From pro- + Latin gestāre (“to bear, to carry”) + -one.

Usage

Often used in medical contexts to refer to the hormone itself or synthetic versions used in therapy.

© 2026 English Reference