English Reference

Word

progesterone

Phoneticspro·ges·terone

US/pɹoʊˈdʒɛstɝˌoʊn/

UK/pɹəʊdʒˈɛstəɹˌəʊn/

Definition

n. a natural hormone in the body that helps manage the menstrual cycle and supports pregnancy.

n. a steroid hormone secreted by the corpus luteum and the placenta that prepares the uterus for the implantation of a fertilized ovum and maintains pregnancy.

Examples

“The doctor checked her progesterone levels during the first trimester.”

“A drop in progesterone levels usually signals the body to begin the menstrual cycle.”

“In addition to its reproductive functions, progesterone acts as a neurosteroid in the brain, influencing mood and sleep patterns through its interaction with various neurotransmitter systems.”

Examples

simple

“The doctor checked her progesterone levels during the first trimester.”

contextual

“A drop in progesterone levels usually signals the body to begin the menstrual cycle.”

complex

“In addition to its reproductive functions, progesterone acts as a neurosteroid in the brain, influencing mood and sleep patterns through its interaction with various neurotransmitter systems.”

Usage

Often used in medical contexts to refer to the hormone itself or synthetic versions used in therapy.

Real-World Examples

“Oestrogen and progesterone are the two main female hormones, and both rise rapidly in pregnancy.”
The Guardian · 22 Aug 2026
“Progesterone rises during the second half of your cycle, before your period begins.”
BBC News · 8 Jul 2026

Etymology

From pro- + Latin gestāre (“to bear, to carry”) + -one.

Etymology adapted from Wiktionary, available under CC BY-SA 4.0.

Word family

This entry

Level
C1 · Advanced
Frequency
Occasional
Updated

Scan code

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English Reference