English Reference

Word

synapse

US/ˈsɪæps/

UK/sˈɪnæps/

Definitions

01nerve junction

C1 · Science

n. the small space between two nerve cells where a message passes from one cell to the next.

n. the functional junction between the axon terminal of one neuron and the dendrite or cell body of another, or an effector cell.

“Chemicals travel across the synapse to carry information between neurons in your brain.”

“The researchers observed how the strength of the synapse changed after repeated stimulation, suggesting a mechanism for long-term memory formation.”

Technical

Usage

Usually functions as a countable noun in biological contexts.

02to connect nerves

C2 · Science

v. to form a connection between nerve cells so signals can pass.

v. to form a synapse or undergo the process of connecting neurons.

“During brain development, billions of neurons begin to synapse with one another.”

“The study aimed to determine the specific conditions under which newly formed neurons synapse with existing circuits in the adult hippocampus.”

Technical

Usage

This verb is intransitive and does not take a direct object.

Synonyms

Real-World Examples

“The new framework proposes that the brain learns these recurring patterns and stores them within networks of synapses.”
ScienceDaily · 18 Aug 2026
“Hibernation cuts down on synapses, but mice seem to retain memories anyway.”
Ars Technica · 22 Aug 2026

Etymology

Learned borrowing from Ancient Greek σύναψις (súnapsis, “conjunction”), from συνάπτω (sunáptō, “to clasp”). Introduced by neurophysiologist Charles Scott Sherrington.

Etymology adapted from Wiktionary, available under CC BY-SA 4.0.

This entry

Level
C1 · Advanced
Frequency
Occasional
Updated

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