English Reference
Noun

degeneration

n. uncountable
C1 Advanced US /dɪˌdʒɛnɝˈeɪʃən/ UK /dɪdʒˌɛnəɹˈeɪʃən/ de·gen·er·a·tion UK spelling degenerations

n.the process of something getting worse or weaker over time. It often describes a part of the body or a part of society that is losing its health or quality.

n.the process of declining from a higher to a lower level of function, structure, or quality. Often refers to the deterioration of tissues in a medical context or the decline of moral standards in a social context.


SIMPLE

The doctor explained the degeneration of the patient's knee joint.

CONTEXTUAL

Urban planners are working to reverse the economic degeneration of the downtown district through new investment.

COMPLEX

While the physical degeneration of the manuscript made some passages illegible, the core of the author's argument remained clear enough for scholars to reconstruct the original thesis.

Usage

Uncountable in its abstract or general sense; can be countable when referring to specific medical instances or types of decline.

Photoreceptor degeneration is behind several major causes of blindness, including age-related macular degeneration (AMD) and retinitis pigmentosa (RP).

ScienceDaily· 28 Aug 2026

Published in Nature Communications , the findings suggest that a DNA repair mechanism may allow Greenland sharks to preserve their eyesight for centuries without showing signs of retinal degeneration.

ScienceDaily· 23 Aug 2026

From French dégénération, from Latin dēgenerātiō.

Etymology adapted from Wiktionary, available under CC BY-SA 4.0.

This entry
Origin Latin dēgenerātiō
Level C1 · Advanced
Frequency Occasional
Updated