English Reference
noun

syndrome

n.
US /ˈsɪnˌdɹoʊm/ UK /sˈɪndɹəʊm/ syn·drome UK spelling syndrome's, syndrome's

  1. 01 C1 Advanced Technical Medicine

    a group of medical signs and symptoms that always happen together and show that someone has a specific illness.

    a recognizable pattern of signs and symptoms that characterize a particular disease or medical condition.

    Simple

    Down syndrome is a genetic condition that affects how a person's body and brain develop.

    In context

    The patient presented with a rare metabolic syndrome that required a multidisciplinary team of specialists to manage effectively.

    Usage

    Often used with a specific name, such as 'Irritable Bowel Syndrome' or 'Chronic Fatigue Syndrome'.

    Teacher's tip

    While often used interchangeably with 'disease' by learners, a syndrome refers specifically to the collection of symptoms rather than the cause itself.

  2. 02 C1 Advanced Academic

    a set of behaviors or feelings that people often show in a specific situation.

    a predictable set of characteristics or behaviors identifying a certain social or psychological condition, often with a negative connotation.

    Simple

    Many new employees suffer from 'imposter syndrome' where they feel they are not good enough for the job.

    In context

    The 'tall poppy syndrome' describes a social phenomenon where people are criticized or resented for their high level of success.

    Usage

    Frequently appears in the structure '[Name] syndrome' to describe a specific social or psychological trend.

    Teacher's tip

    In non-medical contexts, this word is often used to label a specific social problem or a common psychological struggle.

The government estimates that around a third of funding for people with Down Syndrome is spent on social funding.

BBC News· 12 Aug 2026

These two major autism risk genes are also connected to Phelan-McDermid syndrome and other neurodevelopmental disorders.

ScienceDaily· 7 Aug 2026

Learned borrowing from New Latin syndrome, from Ancient Greek συνδρομή (sundromḗ, “concurrence of symptoms, concourse”), from σύνδρομος (súndromos, “running together”), from συν- (sun-, “with”) + δρόμος (drómos, “running, course”).

Etymology adapted from Wiktionary, available under CC BY-SA 4.0.

This entry
Origin Ancient Greek συνδρομή
Level C1 · Advanced
Frequency Common
Updated