know which end is up

arse end of nowhere

A very remote place.

as you know

as it is already known.

big end of town

The top end of town.

bitter end

The end of a long and difficult process.

business end

The part of an object (chiefly a tool or weapon) that is physically used for its operation, rather than some other part such as the part by which it is held.

come to a sticky end

To die unpleasantly due to one's actions.

come to an end

To stop; to cease; to no longer continue.

dead end

A street or path or tunnel that goes nowhere or is blocked on one end.