Word
hydrochloride
Phoneticshy·drochlo·ride
UK/hˈaɪdɹəklˌɔːɹaɪd/
Countable noun
Definition
n. a salt made when a medicine is mixed with hydrochloric acid so it dissolves in water and your body can use it more easily.
n. a salt formed by the reaction of an organic base, typically an amine, with hydrochloric acid, commonly used to improve water solubility and stability of pharmaceutical compounds.
Examples
“The label says the tablet contains fluoxetine hydrochloride.”
“The pharmacist explained that metformin hydrochloride dissolves easily, so the body absorbs the diabetes medicine more reliably.”
“Formulating the drug as a hydrochloride improved its shelf life and solubility, allowing manufacturers to produce a stable tablet that releases the active ingredient predictably in the stomach.”
Examples
simple
“The label says the tablet contains fluoxetine hydrochloride.”
contextual
“The pharmacist explained that metformin hydrochloride dissolves easily, so the body absorbs the diabetes medicine more reliably.”
complex
“Formulating the drug as a hydrochloride improved its shelf life and solubility, allowing manufacturers to produce a stable tablet that releases the active ingredient predictably in the stomach.”
Collocations
Common phrases and expressions where native English speakers use the word “hydrochloride” in context.
Verb
01. administer hydrochloride
“Clinicians administer hydrochloride intravenously in emergency settings.”
verb + noun
02. contain hydrochloride
“These tablets contain hydrochloride to improve solubility and absorption.”
verb + noun
03. dissolve hydrochloride
“Pharmacists dissolve hydrochloride in sterile water before injection.”
verb + noun
04. formulate as hydrochloride
“The compound is formulated as hydrochloride to enhance bioavailability.”
verb + prep + noun
05. hydrochloride dissolves
“Hydrochloride dissolves rapidly in water, ensuring faster onset of action.”
noun + verb
Adjective
06. anhydrous hydrochloride
“Anhydrous hydrochloride was stored sealed to prevent moisture uptake.”
adj + noun
07. crystalline hydrochloride
“The laboratory isolated crystalline hydrochloride for stability testing.”
adj + noun
Noun
08. fluoxetine hydrochloride
“Fluoxetine hydrochloride is used in the treatment of depression and OCD.”
noun + noun
09. administered as lidocaine hydrochloride
“The anaesthetic was administered as lidocaine hydrochloride before the procedure.”
10. contain metformin hydrochloride
“Each tablet contains metformin hydrochloride equivalent to 500 mg metformin.”
11. formulated as hydrochloride salt
“The drug is formulated as a hydrochloride salt to improve solubility.”
12. highly soluble hydrochloride salt
“This highly soluble hydrochloride salt is ideal for oral formulations.”
Usage
Commonly follows the drug name in pharmaceutical names and labels, as in sertraline hydrochloride.
Etymology
From hydro- + chloride.
Etymology adapted from Wiktionary, available under CC BY-SA 4.0.
Word family
NOUN
Related words
- Exam level
- CambridgeCambridgeCambridge English QualificationsThe exam suite from Cambridge University Press & Assessment, from A1 Movers up to C2 Proficiency. The benchmark names double as CEFR labels.C2 ProficiencyIELTSIELTSInternational English Language Testing SystemThe 0–9 band test co-owned by the British Council, IDP, and Cambridge. Used for university entry, work, and migration.8.5–9.0TOEFL iBTTOEFL iBTTest of English as a Foreign Language, Internet-Based TestETS's academic English test, the standard route for US university admissions. Scored 0–120, with a 1–6 scale since 2026.1–6 scale: 6.0114–120
- Frequency
- Occasional
- Level
- C2 · Proficiency
- Updated
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