English Reference

Word

determinant

Phoneticsde·ter·mi·nant, stress on the second syllable

US/dɪˈtɝmənənt/

UK/dɪtˈɜːmɪnənt/

Definition

n. a substance that causes a specific change in a living system. In biology, it is often a chemical that tells a cell what to do or how to grow.

n. a substance that influences or determines a particular biological process or outcome. Often refers to a chemical signal that regulates cellular activity or developmental pathways.

Examples

“The growth hormone is a key determinant of height.”

“Researchers identified a specific protein as the primary determinant of how quickly the cells divide during the early stages of development.”

“While genetics provides the blueprint, environmental factors such as nutrition and stress serve as the primary determinants of how those genes are expressed in the final phenotype.”

Examples

simple

“The growth hormone is a key determinant of height.”

contextual

“Researchers identified a specific protein as the primary determinant of how quickly the cells divide during the early stages of development.”

complex

“While genetics provides the blueprint, environmental factors such as nutrition and stress serve as the primary determinants of how those genes are expressed in the final phenotype.”

Collocations

Common phrases and expressions where native English speakers use the word “determinant” in context.

Adjective

01. important determinant

“Genetic factors are an important determinant of how a cell responds to external stimuli.”

adj + noun

02. key determinant

“The concentration of this protein acts as a key determinant in the cell's growth cycle.”

adj + noun

03. main determinant

“Researchers identified the hormone as the main determinant of the observed biological change.”

adj + noun

04. major determinant

“Environmental pH is a major determinant in the differentiation of these specific stem cells.”

adj + noun

Real-World Examples

“When mapping 81 determinants of fun, “winning” ranked 40th in importance.”
The Guardian 2 Sept 2026
“One of us is a social epidemiologist who studies the social and structural determinants of health, and the other is a prevention scientist who studies risk and protective factors among young people.”
The Conversation 21 Aug 2026
“Northwestern Medicine researchers identified the connection using a new index designed to capture several neighborhood social determinants of health at once.”
ScienceDaily 2 Sept 2026

Etymology

Borrowed from French déterminant, equivalent to determine + -ant.

Etymology adapted from Wiktionary, available under CC BY-SA 4.0.

Word family

NOUN

determinant(C1)

Domain

Biology

This entry

Exam level
CambridgeCambridgeCambridge English QualificationsThe exam suite from Cambridge University Press & Assessment, from A1 Movers up to C2 Proficiency. The benchmark names double as CEFR labels.C1 AdvancedIELTSIELTSInternational English Language Testing SystemThe 0–9 band test co-owned by the British Council, IDP, and Cambridge. Used for university entry, work, and migration.7.0–8.0TOEFL iBTTOEFL iBTTest of English as a Foreign Language, Internet-Based TestETS's academic English test, the standard route for US university admissions. Scored 0–120, with a 1–6 scale since 2026.1–6 scale: 5.0–5.595–113TOEICTOEICTest of English for International CommunicationETS's workplace English test, big in Japan and Korea. Listening & Reading scores 10–990 and tops out at C1.945–990
Frequency
Occasional
Level
C1 · Advanced
Updated

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English Reference