English Reference
Noun

determinant

n.
C1 Advanced US /dɪˈtɝmənənt/ UK /dɪtˈɜːmɪnənt/ de·ter·mi·nant UK spelling determinant's, determinant's Biology

n.a substance that causes a specific change in a living system. In biology, it is often a chemical that tells a cell what to do or how to grow.

n.a substance that influences or determines a particular biological process or outcome. Often refers to a chemical signal that regulates cellular activity or developmental pathways.


SIMPLE

The growth hormone is a key determinant of height.

CONTEXTUAL

Researchers identified a specific protein as the primary determinant of how quickly the cells divide during the early stages of development.

COMPLEX

While genetics provides the blueprint, environmental factors such as nutrition and stress serve as the primary determinants of how those genes are expressed in the final phenotype.

Usage important determinant · key determinant · main determinant

When mapping 81 determinants of fun, “winning” ranked 40th in importance.

The Guardian· 2 Sept 2026

One of us is a social epidemiologist who studies the social and structural determinants of health, and the other is a prevention scientist who studies risk and protective factors among young people.

The Conversation· 21 Aug 2026

Borrowed from French déterminant, equivalent to determine + -ant.

Etymology adapted from Wiktionary, available under CC BY-SA 4.0.

This entry
Level C1 · Advanced
Frequency Occasional
Updated