English Reference

Word

mutate

Phoneticsmu·tate, stress on the first syllable

US/ˈmjuˌteɪt/

UK/mjuːtˈeɪt/

Definition

v. to change into a new form in a deep or lasting way, often because genes change. You use it when a living thing or virus becomes different over time.

v. to undergo or cause a lasting change in genetic structure or essential form. Extends from biology to any fundamental transformation in character or shape.

Examples

“Viruses mutate quickly in crowded places.”

“The flu virus can mutate each winter, so doctors update the vaccine.”

“After decades of isolation, the island plants had mutated into distinct forms with thicker leaves and deeper roots.”

Examples

simple

“Viruses mutate quickly in crowded places.”

contextual

“The flu virus can mutate each winter, so doctors update the vaccine.”

complex

“After decades of isolation, the island plants had mutated into distinct forms with thicker leaves and deeper roots.”

Collocations

Common phrases and expressions where native English speakers use the word “mutate” in context.

Verb

01. mutate cell

“The chemical can mutate cells in the laboratory for research.”

verb + noun

02. mutate dna

“UV light can mutate DNA in skin cells and trigger melanoma.”

verb + noun

03. mutate gene

“Radiation can mutate genes and increase the risk of cancer.”

verb + noun

04. mutate strain

“Scientists fear pollution could mutate strains of common fungi.”

verb + noun

Adjective

05. constantly mutate

“HIV is difficult to treat because it can constantly mutate.”

adv + verb

06. naturally mutate

“Bacteria will naturally mutate over time to survive antibiotics.”

adv + verb

Noun

07. ability to mutate

“The virus's ability to mutate makes it hard to eradicate.”

noun + prep + verb

08. continue to mutate rapidly

“Even after the peak, the virus will continue to mutate rapidly.”

09. mutate beyond recognition

“Over decades, the genetic code could mutate beyond recognition.”

10. mutate into a new strain

“Researchers fear the virus could mutate into a new strain this winter.”

11. mutate to evade immunity

“The pathogen mutated to evade immunity from prior infections.”

12. mutate to resist treatment

“Some tumours mutate to resist treatment and continue growing.”

Usage

Used both intransitively and transitively; takes a direct object when describing a caused change.

Real-World Examples

“With the arrival of the internet, however, memes have become a more tangible phenomenon that can be observed as they grow, spread and mutate.”
BBC Future 29 Sept 2022
“The emergence of this new variant – which is estimated to be 50-75% more transmissible than the original Covid-19 virus – along with others now being detected such as the South African and Brazilian variants, has shone a spotlight on how the coronavirus is mutating as the pandemic rumbles on.”
BBC Future 20 Jan 2021
“The Ebola virus that devastated parts of West Africa over the past year did not mutate at a faster rate than in previous outbreaks, according to an international study published on Wednesday.”
Reuters 17 Jun 2015
“A seasonal flu virus suddenly mutated in the summer.”
BBC 9 Nov 2025

Etymology

First attested in 1796; back-formation from mutation on the basis of -ate (verb-forming suffix), ultimately from Latin mūtō (“to exchange; to change, to vary”). Doublet of moult.

Etymology adapted from Wiktionary, available under CC BY-SA 4.0.

Word family

VERB

mutate(C1)

Related words

This entry

Exam level
CambridgeCambridgeCambridge English QualificationsThe exam suite from Cambridge University Press & Assessment, from A1 Movers up to C2 Proficiency. The benchmark names double as CEFR labels.C1 AdvancedIELTSIELTSInternational English Language Testing SystemThe 0–9 band test co-owned by the British Council, IDP, and Cambridge. Used for university entry, work, and migration.7.0–8.0TOEFL iBTTOEFL iBTTest of English as a Foreign Language, Internet-Based TestETS's academic English test, the standard route for US university admissions. Scored 0–120, with a 1–6 scale since 2026.1–6 scale: 5.0–5.595–113TOEICTOEICTest of English for International CommunicationETS's workplace English test, big in Japan and Korea. Listening & Reading scores 10–990 and tops out at C1.945–990
Frequency
Occasional
Level
C1 · Advanced
Updated

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English Reference