English Reference

Word

glutamate

Phoneticsglu·ta·mate

US/ˈɡɫutəˌmeɪt/

UK/ɡlˈuːtɐmˌeɪt/

Definitions

01chemical salt

C1 · Science

n. a type of chemical salt used in food to make it taste savory or meaty.

n. any salt or ester of glutamic acid, frequently utilized in the food industry as a flavor enhancer.

“Many people recognize monosodium glutamate as the ingredient that gives snacks a savory taste.”

“The food scientist explained that glutamate naturally occurs in aged cheeses and tomatoes, contributing to their intense umami profile.”

Technical

Usage

Often used in the full form 'monosodium glutamate' (MSG) when referring to food additives.

Synonyms

flavor enhancer

02neurotransmitter

C2 · Science

n. a chemical in the brain that helps send messages between nerve cells.

n. the anion of glutamic acid acting as the primary excitatory neurotransmitter in the vertebrate nervous system.

“Glutamate is essential for learning and memory because it helps brain cells communicate.”

“Excessive levels of extracellular glutamate can lead to excitotoxicity, a process where nerve cells are damaged or killed by overactivation.”

Technical

Usage

Uncountable when referring to the chemical substance in a biological context.

Real-World Examples

“Metabotropic glutamate receptors (mGluRs) are found on cells throughout the body and are especially important as modulators of synapses in the brain.”
Phys.org · 14 Sept 2026
“For an NMDA receptor to become fully active, it needs both glutamate and glycine.”
ScienceDaily · 7 Aug 2026

Etymology

From glutamic acid + -ate.

Etymology adapted from Wiktionary, available under CC BY-SA 4.0.

Domain

Chemistry

This entry

Level
C1 · Advanced
Frequency
Occasional
Updated

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English Reference