English Reference

Word

molecule

Phoneticsmol·e·cule, stress on the first syllable

US/ˈmɑɫəkˌjuɫ/

UK/mˈɒlɪkjˌuːl/

Definitions

01chemical unit

B2 · Upper Intermediate Countable noun Science Technical

n. the smallest part of a chemical substance that can exist on its own, made of two or more atoms.

n. the smallest particle of a specific element or compound that retains its chemical properties, consisting of two or more atoms held together by chemical bonds.

“A water molecule is made of two hydrogen atoms and one oxygen atom.”

“The researchers used an electron microscope to observe how each individual molecule reacted when exposed to the new catalyst.”

Usage

Countable noun in scientific contexts.

Synonyms

02a tiny amount

C1 · Advanced Countable noun Literary

n. a very small amount of something.

n. an infinitesimal or extremely small quantity of a substance or quality.

“There was not a single molecule of dust left in the clean room.”

“He did not possess a single molecule of common sense, despite his impressive academic credentials.”

Teaching tip

This sense is often used in negative sentences to emphasize that something is completely missing.

Antonyms

Real-World Examples

“I'm interested in how simple ingredients come together to form bigger and bigger molecules, including those that are building blocks of life.”
Phys.org 16 Aug 2026
“For decades, scientists generally assumed that fossilization destroyed the original organic molecules once present in bones, teeth, and other tissues.”
ScienceDaily 14 Aug 2026
“Nature takes tiny building blocks called atoms and molecules and packs them together to fill up space.”
The Conversation 3 Aug 2026
“The word hydrate means that water molecules are built into the material's structure.”
ScienceDaily 1 Aug 2026

Etymology

Borrowed from French molécule, from New Latin molecula (“a molecule”), diminutive of Latin moles (“a mass”).

Etymology adapted from Wiktionary, available under CC BY-SA 4.0.

Synonyms

Word family

NOUN

molecule(B2)

ADJECTIVE

Related words

Domain

Chemistry

This entry

Exam level
CambridgeCambridgeCambridge English QualificationsThe exam suite from Cambridge University Press & Assessment, from A1 Movers up to C2 Proficiency. The benchmark names double as CEFR labels.B2 FirstIELTSIELTSInternational English Language Testing SystemThe 0–9 band test co-owned by the British Council, IDP, and Cambridge. Used for university entry, work, and migration.5.5–6.5TOEFL iBTTOEFL iBTTest of English as a Foreign Language, Internet-Based TestETS's academic English test, the standard route for US university admissions. Scored 0–120, with a 1–6 scale since 2026.1–6 scale: 4.0–4.572–94TOEICTOEICTest of English for International CommunicationETS's workplace English test, big in Japan and Korea. Listening & Reading scores 10–990 and tops out at C1.785–944
Frequency
Frequent
Level
B2 · Upper Intermediate
Updated

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English Reference